Prediction for Detroit Lions against Miami Dolphins odds, spread, picks, trends for NFL Preseason for game today (1:00 PM ET)

The Dolphins arrive at Week 2 of the NFL preseason with a limp.

Running back Alexander Mattison is out for the year following neck surgery, veteran tackle Germain Ifedi has been placed on injured reserve, and prized edge Chop Robinson was carried off during joint practices. Backup quarterbacks Zach Wilson and Quinn Ewers combined for just 10-for-27 passing last week, with six sacks allowed. Not to mention that Tyreek Hill is currently recuperating from an oblique injury.

Prediction for Detroit Lions against Miami Dolphins odds, spread, picks, trends for NFL Preseason for game today (1:00 PM ET)
Last week, the Lions introduced Kyle Allen, a new quarterback, who completed 7 of 8 passes for 120 yards and two touchdowns. Additionally, Isaac TeSlaa, a novice tight end, made a remarkable touchdown catch. Miami was completely overwhelmed by Detroit’s defense during practice, as they were unable to score on nine consecutive red-zone possessions.

This contest may become increasingly one-sided as Detroit’s first-team defense, and even second-teamers, subject Miami’s offense to periods of three-and-out.


Dolphins vs. Lions Odds, Run Line, and Total

Run Line

Lions +2.5 (-115) Dolphins -2.5 (-105)
Line of credit

Lions (+112) Dolphins (-132)
In total

More than 36.5 (-115)
Under the threshold of 36.5 (-105)
Lions versus Dolphins Instructions for Viewing
Saturday, August 16, 2025
Time: 1:00 p.m. E.T.
Venue: Ford Field
How to Watch (TV): ABC
Dolphins Score: 0-1
Lions Record: 1-1
Lions versus Dolphins Prediction and Selection
In the initial phases of camp, Detroit’s defense has appeared to be legitimately dominant. They have consistently impeded Tua, Wilson, and Ewers through joint practices, despite Miami’s absence of its best receivers. This has resulted in drive-ending takeaway drills and zero red-zone touchdowns on nine opportunities. The execution of your defense is not an accident when it achieves red-zone perfection and records multiple pass-rush takedowns per drill. Dan Campbell is the individual in question.

 

Miami’s running offense and pass protection have been significantly impacted by the abundance of injuries. Frequently, high-profile starters are the driving force behind preseason spreads; however, in this instance, the narrative prioritizes name recognition over actual performance. Detroit’s reserve quarterbacks have demonstrated rhythm and chemistry, while Miami’s backup quarterbacks have committed turnovers and sacks. In the past, teams that dominate joint practices prior to preseason games have a higher likelihood of winning those games. In this case, Detroit’s discipline, defensive strength, efficient quarterback play, and tangible opportunities due to Miami’s creaky offense and depleted backfield all suggest that Detroit will cover on Saturday.

 

Pick: Lions +2.5 (-115 at FanDuel)







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